What Advantage Is There to Phosphoglycerate Kinase Having an Open

Multiple Choice

What advantage is there to phosphoglycerate kinase having an open and closed configuration?

A) It allows water to be trapped in the active site along with the substrate.
B) It forces covalent binding of the substrate to the enzyme active site.
C) The induced-fit mechanism maximizes accessibility of active site without sacrificing hydrophobic environment.
D) Changing of the configuration of the enzyme makes the reaction exergonic.