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Mutations in HGPRT Cause Lesch-Nyhan Syndrome

Question 25

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Mutations in HGPRT cause Lesch-Nyhan syndrome.Mutations can lead to two different outcomes,both of which result in a reduction of guanine salvaging in cells.Contrast the two classes of mutations in HGPRT that can lead to the same result.

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Some mutations decre...

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