All of the Following Are Possible Mechanisms for the Pathogenesis

Multiple Choice

All of the following are possible mechanisms for the pathogenesis in TTP except:

A) TTP plasma is deficient in a platelet-aggregating factor inhibitor
B) Large vWF multimers promote platelet agglutination.
C) Endothelial cell damage via a plasma factor results in platelet adhesion.
D) Inhibition of cyclo-oxygenase (aspirin-like)
E) Deficiency of prostacyclin (PGI₂) synthesis and release leading to platelet aggregation and thrombosis