A Biologist Wants to Compare the Integral Membrane Protein Content

Multiple Choice

A biologist wants to compare the integral membrane protein content of cells from mouse liver, pancreas, and intestine.Which experimental procedure should she choose?

A) Compare the patterns of bumps observed when cells of each type are subjected to freeze-fracture electron microscopy.
B) Perform three cell fusion experiments in which each cell type is labeled, fused with another labeled cell, and observed to see how rapidly the labels mix together.
C) Hold mice in environments of varying temperatures, then analyze and compare the fluidities of membranes isolated from each cell type.
D) Treat intact cells with enzymes that hydrolyze peptide bonds, then test whether the cells have lost their ability to bind to various small molecules, such as glucose.
E) Carry out chemical analyses of the phospholipid composition of membranes isolated from each cell type, then compare the results.