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Refer to the Figure and Table Below

Question 187

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Refer to the figure and table below. Refer to the figure and table below.     Vitamin B<sub>12</sub> is an essential vitamin that humans must acquire from their diets.Within the small intestine, vitamin B<sub>12</sub> is taken up by receptor-mediated endocytosis as shown in the figure.The protein labeled IF binds to vitamin B<sub>12</sub> molecules in the intestinal lumen, forming a complex.This complex is recognized by the IF receptor present on intestinal cells and stimulates endocytosis when it binds.Vitamin B<sub>12</sub> by itself does not bind to the receptor.Individuals known to carry a mutation in either the IF protein or the IF receptor are represented in the table, along with observations about whether symptoms of vitamin B<sub>12</sub> deficiency are present.If a drug molecule could be produced that would bind to vitamin B<sub>12</sub> and stimulate uptake by intestinal cells, which individual(s)  would be expected to benefit, based on the information given? A)  Individual 1 only B)  Individual 2 only C)  Individual 3 only D)  Individuals 1 and 2 only E)  Individuals 2 and 3 only Refer to the figure and table below.     Vitamin B<sub>12</sub> is an essential vitamin that humans must acquire from their diets.Within the small intestine, vitamin B<sub>12</sub> is taken up by receptor-mediated endocytosis as shown in the figure.The protein labeled IF binds to vitamin B<sub>12</sub> molecules in the intestinal lumen, forming a complex.This complex is recognized by the IF receptor present on intestinal cells and stimulates endocytosis when it binds.Vitamin B<sub>12</sub> by itself does not bind to the receptor.Individuals known to carry a mutation in either the IF protein or the IF receptor are represented in the table, along with observations about whether symptoms of vitamin B<sub>12</sub> deficiency are present.If a drug molecule could be produced that would bind to vitamin B<sub>12</sub> and stimulate uptake by intestinal cells, which individual(s)  would be expected to benefit, based on the information given? A)  Individual 1 only B)  Individual 2 only C)  Individual 3 only D)  Individuals 1 and 2 only E)  Individuals 2 and 3 only Vitamin B12 is an essential vitamin that humans must acquire from their diets.Within the small intestine, vitamin B12 is taken up by receptor-mediated endocytosis as shown in the figure.The protein labeled IF binds to vitamin B12 molecules in the intestinal lumen, forming a complex.This complex is recognized by the IF receptor present on intestinal cells and stimulates endocytosis when it binds.Vitamin B12 by itself does not bind to the receptor.Individuals known to carry a mutation in either the IF protein or the IF receptor are represented in the table, along with observations about whether symptoms of vitamin B12 deficiency are present.If a drug molecule could be produced that would bind to vitamin B12 and stimulate uptake by intestinal cells, which individual(s) would be expected to benefit, based on the information given?


A) Individual 1 only
B) Individual 2 only
C) Individual 3 only
D) Individuals 1 and 2 only
E) Individuals 2 and 3 only

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