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A Mutation in the Thyroid-Stimulating Hormone Receptor (TSH Receptor) Results

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A mutation in the thyroid-stimulating hormone receptor (TSH receptor) results in a change in the behavior of the receptor toward its ligand, thyroid-stimulating hormone (TSH).Explain what measuring the TSH dissociation constant, KD, will reveal about this behavior, and explain how a change in this value will affect cells that have this receptor embedded in their cell membranes.

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Measuring the KD will reveal any changes ...

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