Essay
Refer to the figure below. It has been hypothesized that during development of the mammalian brain, neurons are first coupled through gap junctions to one another during the first few days after birth.These gap junctions provide a conduit for propagation of electrical activity as a flow of ions between neurons, as depicted in the figure on the left.However, it is thought that these gap junctions are replaced after this initial period with a chemical signaling system, as depicted in the figure on the right.This system involves one neuron secreting neurotransmitter compounds that carry the signal across the extracellular space to an adjacent neuron, where the electrical signal is continued.Design an experiment to test the hypothesis that gap junctions are replaced during the early days after birth.You may use rats and the compound halothane in your design.Halothane is a compound known to specifically bind to and block gap junctions.
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