During the Metabolism of Glucose, the Conversion of Glucose to Glucose

Multiple Choice

During the metabolism of glucose, the conversion of glucose to glucose 6-phosphate cannot proceed without the hydrolysis of ATP.Which is a reason for this?

A) Chemical energy can only be converted to chemical energy.
B) Glucose 6-phosphate has a lower free energy than glucose.
C) The reaction is spontaneous.
D) The reaction involves a large decrease in free energy.
E) The reaction is endergonic.