Which Statement Regarding Allosterically Regulated Enzymes Is Valid

Multiple Choice

Which statement regarding allosterically regulated enzymes is valid?

A) Allosterically regulated enzymes often have more than one subunit.
B) An allosteric enzyme is locked in a rigid conformation, indicating that it cannot use induced-fit mechanisms for catalyzing reactions.
C) The allosteric regulatory sites overlap with the active site in an allosteric enzyme.
D) Unlike substrate binding, the binding of molecules to allosteric sites in an allosteric enzyme is nonspecific.
E) The only type of effect of an allosteric molecule on an allosteric enzyme is an inhibitory effect.