Which Transfusion Is Most Likely to Cause an Immune Reaction

Multiple Choice

Which transfusion is most likely to cause an immune reaction?

A) A transfusion of O type blood to a person with A type blood
B) A transfusion of A type blood to a person with O type blood
C) A transfusion of B type blood to a person with AB type blood
D) A transfusion of O type blood to a person with O type blood
E) A transfusion of AB type blood to a person with AB type blood