Essay
The nucleoside analogue acyclovir, which is used to treat herpes simplex virus (HSV) infections, lacks a 3 hydroxyl group (-OH).Predict what will happen if the host cell DNA polymerase incorporates a molecule of acyclovir into an elongating strand of HSV DNA.
a. Acyclovir will block the activity of the DNA helicase.
b. The DNA polymerase will only incorporate acyclovir molecules.
c. The replication complex will no longer bind to origins of replication.
d. DNA polymerase will not be able to link a successive nucleotide.
e. Acyclovir will bind single-strand binding proteins.
Correct Answer:
Verified
Correct Answer:
Verified
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