Which Statement Does Not Support Garrod's Hypothesis That Inborn Errors

Multiple Choice

Which statement does not support Garrod's hypothesis that inborn errors of metabolism cause disease?

A) The disease PKU is due to failure to produce a functional variant of an enzyme.
B) A blood disease is due to a recessive allele in a single gene.
C) A neurological disease is due to a dominant allele in a single gene.
D) Multiple genes contribute to the likelihood that a person will develop coronary heart disease.
E) Supplying a patient with a missing enzyme can alleviate the symptoms of a metabolic disease.