A Disease That Manifests Itself in Symptoms of Neurodegeneration Is

Multiple Choice

A disease that manifests itself in symptoms of neurodegeneration is passed down from generation to generation in a manner consistent with an autosomal dominant mutation.The symptoms tend to get worse in subsequent generations, with individuals showing symptoms at progressively earlier ages than their afflicted parents.What is the most reasonable hypothesis consistent with all of these facts?

A) The mutation is due to a reciprocal translocation.
B) The disease is due to many different mutations.
C) The mutated gene contains an expanding triplet repeat.
D) The mutated gene is a dominant loss-of-function mutation.
E) The mutation is due to an insertion of a transposon.