When Can Variation at SNPs Be Detected Using Standard Gel

Multiple Choice

When can variation at SNPs be detected using standard gel electrophoresis?

A) When a large amount of DNA is used
B) When the SNP is at a restriction site and the corresponding restriction enzyme is used in the experiment
C) Only when using allele-specific oligonucleotide hybridization
D) When using PCR amplification
E) Variation at SNPs cannot be detected using gel electrophoresis