Children Born with Two Nonfunctional RB Genes Will Develop Retinoblastoma

Multiple Choice

Children born with two nonfunctional RB genes will develop retinoblastoma, a retinal tumor.The mutations that result in nonfunctional RB protein include the following types of mutations.Which mutation represents a SNP in the coding sequence of the gene?

A) Nonsense mutation
B) Frame-shift mutation
C) Intron mutation
D) In-frame deletion
E) Promoter mutation