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An Enzyme Is Required to Convert the Inactive Form of a Drug

Question 127

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An enzyme is required to convert the inactive form of a drug into the active form.A completely dominant change from the G to the C allele increases activity of the enzyme.Too much of the active form of the drug can lead to tremors.Too little of the active form of the drug renders it ineffective.Which scenario is most likely?


A) Individuals with the GC genotype are more likely to have tremors from the drug than those with CC.
B) Individuals with the GC genotype are more likely to have tremors from the drug than those with GG.
C) The drug is more likely to be ineffective in individuals with the GC genotype than in those with GG.
D) The drug is more likely to be just as effective in individuals with the GC genotype as in those with CC.
E) The drug is less likely to be ineffective in individuals with the GG genotype than those with GC.

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