Which Statement Is False

Multiple Choice

Which statement is false?

A) The cellular components of blood are generated by stem cells in the bone marrow.
B) The kidneys express hypoxia-inducible factor 1 (HIF-1) in response to hypoxia.
C) Increases in circulating levels of erythropoietin extend the lives of mature red blood cells.
D) Major sites of red blood cell production include bone marrow of the ribs, pelvis, and vertebrae.
E) Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that inactivates the gene encoding erythropoietin.