Matching Questions

Short Answer

Matching questions.In the space provided, indicate the letter corresponding to the most appropriate term that is defined or described below.
a.blood-brain barrier
b.agonist
c.enzyme
d.pharmacokinetics
e.efficacy
f.clinical efficacy
g.ion
i.metabolism
j.therapeutic index
k.pharmacodynamics
l.potency
m.physiological antagonism
1) _____ Study of the biochemical and physiological effects of drugs and their mechanisms of action.
2) _____ Refers specifically to the dose at which the effect occurs.
3) _____ A drug's relative margin of safety.
4) _____ Refers to the relative capability of an agent to activate a receptor after binding with the receptor.
5) ____ The processes involved in a drug's absorption, distribution, binding or localization in tissues, metabolic alterations, and excretion from the body.
6) _____ Structurally consisting of tightly packed endothelial cells of brain capillaries, surrounded by a very lipid sheath made up of extensions of "glial feet" from nearby astrocyte cells, which prevent non-lipid-soluble (most non-nutritive) substances from entering the central nervous system.
7) _____ A protein secreted by cells that acts as a catalyst to induce chemical changes in other substances, but which itself is unchanged in the process.