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Isosorbide Dinitrate Is a Long-Acting Nitrate Given Twice Daily

Question 4

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Isosorbide dinitrate is a long-acting nitrate given twice daily. The schedule for administration is 7 a.m. and 2 p.m. because:


A) Long-acting forms have a higher risk for toxicity.
B) Orthostatic hypotension is a common adverse effect.
C) It must be taken with milk or food.
D) Nitrate tolerance can develop.

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