A Bone Marrow Transplant May Not Be Appropriate from a Given

Multiple Choice

A bone marrow transplant may not be appropriate from a given donor (Jane) to a given recipient (Jane's cousin Bob) , even though Jane has previously given blood for one of Bob's needed transfusions, because ________.

A) Jane's major histocompatibility (MHC) proteins may not be a match
B) a blood-type match is less stringent than a match required for transplant because blood is more tolerant of change
C) Jane is heterozygous for MHC genes but Bob is not
D) Jane's MHC class II genes are not expressed in bone marrow
E) Bob's immune response is impaired