The Fact That an Enzyme-Catalyzed Reaction Is First Order with Respect

Multiple Choice

The fact that an enzyme-catalyzed reaction is first order with respect to substrate at low substrate concentration but becomes zero order with respect to substrate at high substrate concentration is explained by

A) the catalytic constant.
B) reversibility of formation of the enzyme-substrate complex.
C) three point attachment.
D) specificity.
E) saturation.