Koshland Has Proposed the Induced Fit Theory of Enzyme Action

Multiple Choice

Koshland has proposed the induced fit theory of enzyme action. This concept implies that:

A) the template or lock-and-key theory adequately explains the mechanism of enzyme catalysis.
B) the active site is flexible; the catalytic group(s) of the enzyme is/are brought into proper alignment by the substrate.
C) the conformation of the substrate changes before binding to the enzyme.
D) the formation of the enzyme-substrate complex is always the fastest step in an enzyme catalyzed reaction.