The Initial Velocity Condition in the Derivation of the Michaelis-Menten

Multiple Choice

The initial velocity condition in the derivation of the Michaelis-Menten expression

A) allows measurement of product formation near equilibrium.
B) may not be attainable if the equilibrium constant is very large in favor of product formation.
C) requires that measurements be made before product accumulates significantly.
D) requires that the enzyme-substrate complex be formed very slowly.
E) none of the above