A Gain of Function Mutation to a Gene Encoding a Protein

Multiple Choice

A gain of function mutation to a gene encoding a protein in a signal transduction pathway

A) cannot involve the genes encoding heterotrimeric guanine nucleotide-binding proteins.
B) causes constitutive activation of signal transduction.
C) is characterized by a measurable increase in the circulating concentration of the specific hormone agonist.
D) is invariably germ?line in origin.