As Regards Receptor? Mediated Hydrolysis of Phosphatidylinositol, Which of the Following

Multiple Choice

As regards receptor? mediated hydrolysis of phosphatidylinositol, which of the following statements, if any, is/are true?

A) Activated Protein Kinase C activates the transcription factor NF Kappa B by directly phosphorylating it which allows its release from I Kappa B (the cytosolic inhibitor) .
B) Protein Kinase C activity is directly stimulated by calcium and IP3.
C) In receptors coupled to the PI cycle but not containing an intrinsic tyrosine kinase activity, the two second messengers of the PI cycle are released by the enzyme phospholipase C Gamma?l
D) All of the above.
E) None of the above.