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Why Is the Hydrolysis of GTP by a G-Protein Essentially

Question 17

Multiple Choice

Why is the hydrolysis of GTP by a G-protein essentially irreversible?


A) GDP immediately hydrolyzes to GMP and Pi
B) GDP is metabolized to cGMP
C) GDP remains bound after Pi is liberated
D) GTP cannot be synthesized from GDP
E) The Km for Pi is too low

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