Under What Circumstance Might Measuring the Frequency of Homozygous Recessive

Multiple Choice

Under what circumstance might measuring the frequency of homozygous recessive genotypes lead to erroneous predictions of allele frequencies in a population?

A) The population is under Hardy-Weinberg equilibrium.
B) The population is affected by heterozygote advantage.
C) The population has undergone genetic drift in the past.
D) The population is affected by homozygote advantage.