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The Folding Cycle in the GroES-GroEL Complex of E

Question 34

Multiple Choice

The folding cycle in the GroES-GroEL complex of E. coli utilizes the following sequence:
A.ATP binding to GroEL
B.GroES dissociates from the complex
C.Partially folded protein hydrophobic residues bind GroEL
D.GroES is recruited to GroEL
E.GroES promotes ATP hydrolysis and α-subunits undergo a conformational change that buries the hydrophobic patches


A) A, B, C, D, E
B) B, A, C, D, E
C) C, D, A, E, B
D) C, A, D, E, B
E) D, C, E, A, B

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