Enzymatic Ribonucleotide Reduction Is Accomplished Via a Free Radical Mechanism

Multiple Choice

Enzymatic ribonucleotide reduction is accomplished via a free radical mechanism. Which of the following statements is true regarding this process?

A) The substrate specificity site on the R1 homodimer determines if the enzyme is active or inactive.
B) R2 has a single active site containing two Fe atoms that generate the free radicals required for reduction.
C) R2, but not R1, function in the delivery of reducing equivalents.
D) R2 homodimer carries two regulatory sites.
E) A final decarboxylation forms the deoxyribonucleotide product.