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Polylysine Is a Random Coil When the PH Is Less

Question 30

Multiple Choice

Polylysine is a random coil when the pH is less than 11, while it forms an α-helix if the pH is raised to greater than 12. This is because at pH 12:


A) the lysine residues are negatively charged which electrostatically stabilizes the helix.
B) the positive charges on the lysine residues stabilizes the α-helix.
C) the lysine residues are neutral which eliminates electrostatic repulsion between the R groups.
D) the high concentration of OH− ions in solution reduces the electrostatic repulsion between the R-groups.
E) the lysine side chain changes configuration with pH.

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