Which of the Following Observations Helps to Explain the Conformational

Multiple Choice

Which of the following observations helps to explain the conformational changes that occur in hemoglobin upon binding to oxygen?

A) The four heme groups are positioned close to the surface of the molecule.
B) An αβ dimer rotates and slides with respect to the other dimer upon binding oxygen.
C) Neither the heme nor the iron ion in the deoxy conformation is in a planar conformation.
D) All of the above
E) B and C