What Experimental Evidence Suggests That the N-Terminal Tails of Histones

Multiple Choice

What experimental evidence suggests that the N-terminal tails of histones participate in the formation of higher-order chromatin structure?

A) The tails cause histones to denature.
B) The tails when acetylated cause the dissolution of the 30-nm fibers.
C) Chromatin fibers prepared with H4 histones lacking their tails cannot fold into higher-order fibers.
D) Chromatin fibers prepared with H4 histones possessing longer tails cannot fold into higher-order fibers.
E) Chromatin fibers lacking tails are shorter.