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Which Cells in the Pancreas Produce the Enzymes Responsible for Digestion

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Which cells in the pancreas produce the enzymes responsible for digestion of food in the intestine? What do pancreatic beta cells do? What treatment was used to cause the reprogramming of pancreatic acinar cells into pancreatic beta cells? How did the researchers know that the transdifferentiation had,in fact,occurred and resulted in the production of more pancreatic beta cells? Why is the use of adenoviruses to deliver the genes in this experiment less of a risk in humans than using some other viruses would be?

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