Which of the Following Statements About Negative Selection During Lymphocyte

Multiple Choice

Which of the following statements about negative selection during lymphocyte development is most accurate?

A) The mechanism of negative selection is the death of cells whose antigen receptors are not stimulated by self antigens.
B) The mechanism of negative selection is apoptosis actively induced by antigen-receptor recognition of self antigens.
C) Negative selection ensures a self MHC restricted repertoire of T lymphocytes.
D) Negative selection occurs only in T cell maturation and not in B cell maturation.
E) The major mechanism of negative selection is inhibition of antigen receptor expression.