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The Tumor Necrosis Factor (TNF)family of Proteins Includes Several Soluble

Question 6

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The tumor necrosis factor (TNF) family of proteins includes several soluble and membrane proteins that share structural homologies.All members of this family bind to members of the TNF-receptor family of molecules expressed on cell surfaces.TNF-R family members are structurally homologous to one another and utilize similar signal transduction pathways.
For each description of a TNF or a TNF-R family member in questions ,select the term listed in options A-E that best matches it.
-Expressed on macrophages and B lymphocytes,this receptor plays an important role in the helper T cell-mediated effector functions.


A) TNF-RI
B) CD40
C) Fas ligand
D) RANK
E) Lymphotoxin/TNF-b

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