Large Clinical Trials Have Been Performed to Compare the Vaccine

Multiple Choice

Large clinical trials have been performed to compare the vaccine efficacy of the live-attenuated influenza virus vaccine with that of the inactivated virus vaccine. In all, data from over 25,000 children aged 6-71 months were analyzed. The conclusion was that the children who received the live-attenuated vaccine reported 50% fewer cases of influenza than those who received the inactivated vaccine. One difference in the immune response elicited by the live-attenuated versus the inactivated vaccine is:

A) The live-attenuated vaccine elicits higher antibody titers than the inactivated vaccine.
B) The live-attenuated vaccine elicits antibodies with higher affinities than the inactivated vaccine.
C) The live-attenuated vaccine elicits increased numbers of CD4 T_FH cells than the inactivated vaccine.
D) The live-attenuated vaccine elicits antiviral CD8 effector responses but the inactivated vaccine does not.
E) The live-attenuated vaccine induces antibodies of the IgA isotype, but the inactivated vaccine does not.