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In Some Vertebrates, Such as Rays and Some Shark Species

Question 4

Multiple Choice

In some vertebrates, such as rays and some shark species, immunoglobulin light chain genes consist of multiple units of already rearranged VJ-C genes, of which one is chosen for expression in a developing B cell. This strategy may have evolved in these organisms:


A) Prior to the evolution of rearranging gene segments requiring somatic recombination in developing B cells
B) Prior to the evolution of the RAG1 and RAG2 enzymes needed for recombination
C) As a mechanism to increase light chain diversity beyond that achieved by the use of rearranging gene segments in humans
D) As a mechanism to increase light chain diversity beyond that achieved the gene conversion process used in chickens
E) As a means to generate a rapid response to common pathogens encountered by these animals

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