The Side Chain (R Group) of the Amino Acid Serine

Multiple Choice

The side chain (R group) of the amino acid serine is -CH2-OH. The side chain of the amino acid leucine is -CH2-CH-(CH3) 2. Where would you expect to find these amino acids in a globular protein in aqueous solution?

A) Serine would be on the exterior, and leucine would be in the interior of the globular protein.
B) Serine would be in the interior, and leucine would be on the exterior of the globular protein.
C) Both serine and leucine would be in the interior of the globular protein.
D) Both serine and leucine would be on the exterior of the globular protein.