Pax-6 Usually Causes the Production of a Type of Light-Receptor

Multiple Choice

Pax-6 usually causes the production of a type of light-receptor pigment. In vertebrate eyes, though, a different gene (the rh gene family) is responsible for the light-receptor pigments of the retina. The rh gene, like Pax-6, is ancient. In the marine ragworm, for example, the rh gene causes production of c-opsin, which helps regulate the worm's biological clock. Which of these most likely accounts for vertebrate vision?

A) The Pax-6 gene mutated to become the rh gene among early mammals.
B) During vertebrate evolution, the rh gene for biological clock opsin was co-opted as a gene for visual receptor pigments.
C) In animals more ancient than ragworms, the rh gene(s) coded for visual receptor pigments; in lineages more recent than ragworms, rh has flip-flopped several times between producing biological clock opsins and visual receptor pigments.
D) Pax-6 was lost from the mammalian genome, and replaced by the rh gene much later.