What Is the Basis for the Difference in How the Leading

Multiple Choice

What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?

A) DNA polymerase can join new nucleotides only to the 3' end of a preexisting strand.
B) Helicases and single-strand binding proteins work at the 5' end.
C) The origins of replication occur only at the 5' end.
D) DNA ligase works only in the 3' → 5' direction.