The Rate of Mutation to a Recessive Lethal Allele Is

Multiple Choice

The rate of mutation to a recessive lethal allele is 0.000001. What is the equilibrium frequency this allele? (Recall that the equilibrium frequency for a recessive allele under mutation-selection balance is q =  s, where  is the rate of mutation to the disease allele and s is the selection coefficient against that allele. In the case of a lethal allele, s  1.)

A) 0.001
B) 0.000001
C) 0.1
D) 1.0