Essay
In the general population, 1 in 300 individuals is a carrier for Tay-Sachs disease, while 1 in 30 individuals of Ashkenazi Jew descent are carriers. Tay-Sachs also affects 1 in 30 individuals with French-Canadian ancestry, although two completely unique mutations are responsible for the Ashkenazi and French-Canadian mutations. What are the chances of two individuals who are carriers having a child with Tay-Sachs if
a. both individuals are not of Ashkenazi or French-Canadian descent?
b. one individual is of Ashkenazi descent and one is not?
c. both individuals are of Ashkenazi descent?
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