Ingram Examined Hemoglobin Structural Variation by Breaking Down the Hemoglobin

Multiple Choice

Ingram examined hemoglobin structural variation by breaking down the hemoglobin protein into many fragments by chemical treatment and subjecting the fragments to electrophoresis to separate them in a gel; and then in a second dimension, perpendicular to the first, he separated them by chromatography. This two-step approach is commonly referred to as __________.

A) hybridization
B) electrophoretic mobility
C) densitometry
D) restriction fragment analysis
E) peptide fingerprint analysis