Which Statement Is NOT True About Base Stacking When Nucleic

Multiple Choice

Which statement is NOT true about base stacking when nucleic acids are in a double-stranded conformation?

A) Stacking interactions occur when two or more bases are positioned with their rings parallel to each other.
B) Stacking interactions are hydrophilic in nature.
C) Stacking involves a combination of van der Waals and dipole-dipole interactions between bases.
D) Base stacking helps to minimize contact of the bases with water.
E) Base stacking interactions are important in stabilizing the three-dimensional structure of nucleic acids.