Retroviral Genomes Tend to Mutate at a Very High Rate

Multiple Choice

Retroviral genomes tend to mutate at a very high rate. What statement BEST explains this observation?

A) The RNA genome is highly susceptible to chemical damage.
B) Specific enzymes in cells will modify the genome as a protection against infection.
C) RNA phosphodiester bonds will tend to hydrolyze spontaneously.
D) The virus changes the sequence to prevent antibody binding to the viral genome.
E) Reverse transcriptase lacks a 3' to 5'exonuclease activity.