Why Is Flux Through the Citric Acid Low in the Resting

Multiple Choice

Why is flux through the citric acid low in the resting state?

A) Flux through the cycle is low due to a drop in serum adrenaline levels.
B) Flux through the cycle is low due to allosteric inhibition of pyruvate carboxylase.
C) Flux through the cycle is low due to complete oxidation of NADH because oxygen is readily available.
D) Flux through the cycle is low due to low local concentrations of NAD⁺ because of a diminished rate of oxidative phosphorylation.
E) Flux through the cycle is low due to product inhibition of the pyruvate dehydrogenase complex by ATP.