Suppose That Three Critical Amino Acids in the Active Site

Multiple Choice

Suppose that three critical amino acids in the active site of a specific enzyme are threonine, serine, and glutamic acid. Which of the following characteristics would you predict the substrate to possess in order to bind the active site of this enzyme?

A) relatively hydrophobic
B) hydrophilic, with a negative charge
C) hydrophilic, with a positive charge
D) hydrophilic, but without a charge