Derivatives of the Compound Shown Below Are Currently Being Examined

Multiple Choice

Derivatives of the compound shown below are currently being examined for their effectiveness in treating drug addiction and metabolic syndrome (J. Med. Chem. 2006, 872) . Which sequence ranks the following aromatic rings of this compound in order of increasing reactivity in an electrophilic aromatic substitution reaction (slowest to fastest reacting) ?

A) 1 < 2 < 3
B) 2 < 3 < 1
C) 3 < 2 < 1
D) 3 < 1 < 2
E) 2 < 1 < 3