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It Has Been Difficult to Develop Drugs for Brain Disorders

Question 27

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It has been difficult to develop drugs for brain disorders including AD. For example, many groups have tried to target γ-secretase.
A. Why is γ-secretase a good target for Alzheimer's treatment?
B. What is one reason, so far, that drugs targeting γ-secretase have not been successful?

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γ-secretase is the enzyme that produces ...

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