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Infusion of Oxytocin into the Brain of an Ovariectomized (Unreceptive)

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Infusion of oxytocin into the brain of an ovariectomized (unreceptive) female prairie vole is sufficient for her to develop preference for a nearby male. But what is the neurological basis for this preference? There are established techniques for making knockout and transgenic mice, but since mice do not exhibit pair-bonding behavior, researchers are currently developing similar techniques for use in voles. Describe some specific experiments that you would like to perform in order to determine in which neurons oxytocin reception is present, necessary, and sufficient for female vole partner preference.

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You could use radioactively labeled oxyt...

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